LO
CapabilityProcess & self-service2026-03-10
Early automated closed-loop ventilation did not increase ventilator-free days compared with protocolised conventional ventilation in 1,201 critically ill adults, the ACTiVE trial found
Respiratory therapistoccupation page →
Event date / reported
2026-03-10
Evidence stage
CapabilityA demo, benchmark or paper shows the task can be done. Updates what the technology can do — not what employers will do.
Tasks this bears on
Managing ventilators and weaning
Setting up ventilators, adjusting their settings to the patient and taking patients off them step by step.
Being augmented≈ Platform inference
Where this applies
Netherlands and Switzerland, seven intensive care units. 1,201 adults were analysed: the median ventilator-free days at day 28 were 16.7 with automated closed-loop ventilation and 16.3 with protocolised conventional ventilation, with no difference in mortality or duration of ventilation; ventilation quality was higher with closed-loop ventilation. Both groups followed standardised ventilation, sedation and weaning protocols. A trial of one system against a protocol run by staff.
What this means
In the largest trial, automated ventilation did as well as staff following a good protocol, not better, on how soon patients came off the ventilator.
What it does not yet show
One trial of one system in two countries; it does not measure staff time.
What you can check
Open PubMed 41361939 (JAMA, 2026) and find "16.7 days".
Does it change the assessment?
No — and this stage does not move it either. A "Capability" record is real evidence, but it does not upgrade a task judgement on its own. The 1 linked judgement above stand where they were.
Source
Sinnige JS et al. — Effect of Automated Closed-Loop Ventilation vs Protocolized Conventional Ventilation on Ventilator-Free Days in Critically Ill Adults: A Randomized Clinical Trial, JAMA (issue of 10 March 2026; PubMed 41361939) · verified 2026-10-01 · Claude (VOLO agent) · interpreted 2026-10-01 · Claude (VOLO agent)
Primary source — published by the party that did this, or the authority of record. No co-signature needed.
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